https://nova.newcastle.edu.au/vital/access/ /manager/Index en-au 5 https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:45183 Wed 26 Oct 2022 14:32:09 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:30922 Wed 24 Nov 2021 15:50:56 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:18342 Wed 24 Jun 2015 12:25:31 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:46469 0.75) was found for mean, peak, and peak to peak amplitude for healthy people. Only mean amplitude demonstrated good intratester reliability in those with CNLBP. Peak amplitude and peak to peak amplitude of the gluteus medius muscle of those with CNLBP, and the time of peak amplitude in both groups, demonstrated moderate reliability (ICC ranged from 0.50 to 0.58). Moderate to large standard error of measurement and minimal detectable change values were reported for outcome measurements. These results suggest that potentially large levels of random error can occur between sessions. Future research can build on this study for those with pathology and attempt to establish change values for EMG that are clinically meaningful.]]> Wed 23 Nov 2022 14:53:17 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:31015 Wed 17 Nov 2021 16:28:49 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:37968 Wed 14 Jul 2021 13:44:32 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:40302 Wed 13 Mar 2024 08:50:00 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:53451 Wed 13 Mar 2024 07:51:29 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:13395 Wed 11 Apr 2018 17:06:14 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:16778 Wed 11 Apr 2018 12:49:08 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:11798 Wed 11 Apr 2018 11:56:09 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:11874 Wed 11 Apr 2018 11:35:52 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:11875 Wed 11 Apr 2018 11:01:05 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:23221  0.05), Social Function (r s = 0.219, p < 0.05) and the Physical Component Summary score (r s = 0.203, p < 0.05). Conclusions: The toe brachial index demonstrates limited associations with physical and social aspects of health-related quality of life in older people.]]> Wed 11 Apr 2018 09:33:18 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:49278 12 weeks' duration8. Chronic DFU patients are more likely to undergo amputation as they are more prone to infection and wound deterioration over time5. AIMS: In order to determine which factors are contributing most to delayed healing in patients with DFU, we need to conduct a prospective cross-sectional study that will measure all of the major factors implicated in wound chronicity in DFU (Figure 1) and determine the effect each of these have on wound Wound Practice and Research 112 healing time and outcomes, including amputation. Therefore the aims of our study are primarily to assess factors contributing to healing outcomes and wound chronicity in people with DFU and secondarily to measure dietary intake in patients with DFU in an Australian setting. METHOD: Participants with diabetes (type 1 and 2) and current DFU attending a public health podiatry clinic will be included and will attend a single testing session. Exclusion criteria will include a contraindication for placement of the toe cuff around the hallux or second digit, previous bilateral mastectomy preventing brachial blood pressure examination, vasospastic disorders, an inability to adhere to the testing protocol, and/or an inability to give informed consent. During a 12-month period it is expected 144 participants will be from across three sites (Hunter New England High Risk Foot Clinic, Wyong High Risk Foot Clinic and Gosford High Risk Foot Clinic), with 60 participants recruited to date. In order to determine which factors are contributing to delayed healing outcomes, a number of variables will bemeasured. A current general medical history will be obtained from the participants’ general practitioner, including current medication, concurrent chronic disease status, overall general medical history and diabetes duration, type (1 or 2), and current HbA1c levels. HbA1c levels are reflective of glycaemia over 2-3 months and are associated with wound healing rates in patients with diabetes. Higher HbA1c levels are associated with poorer healing outcomes – with each 1.0% increase in HbA1c, a daily reduction in wound healing of 0.028 cm2 can be expected9. Demographic data, including age, gender and smoking status, will also be collected. Nicotine is a vasoconstrictor which reduces skin blood flow, resulting in localised tissue ischaemia and impaired healing capability10. Smoking has therefore been clinically associated with general delayed healing; however, extensive controlled studies are yet to be undertaken in DFU. This study will determine if – and to what level – smoking has an effect on healing outcomes in DFU. Lower limb vascular assessment will include systolic toe pressure measurement along with a toe-brachial pressure index, both of which have been demonstrated as accurate indicators of PAD in patients with diabetes11,12. The presence of PAD and its negative impact on healing capacity is frequently underestimated, with the presence of ischaemia within a DFU not always obvious. That is, whilst purely ischaemic ulcers are readily identified by their characteristic appearance, symptoms and location, neuro-ischaemic DFUs can be more subtle in presentation13,14. This study will therefore aim to establish how much impact PAD has on healing outcomes in DFU. An assessment of dietary intake will also be conducted by using the Australian Eating Survey (AES), a valid and reproducible method of quantifying dietary intake15 that assesses usual food and nutrient intake over the preceding 3-6 months. Wound healing requires adequate dietary intake, with poor healing outcomes associated with deficiencies in nutrition16. Nutrition deficiencies can negatively impact Fig 1: Factors influencing wound chronicity in DFU Chronic diabetic foot ulceration Foot deformity/ Offloading Vascular Supply Peripheral neuropathy Glycaemic Control Wound Severity Infection Physical factors including smoking, BMI Dietary IntakeFigure 1. Factors influencing wound chronicity in DFU Tehan et al. Factors contributing to wound chronicity in diabetic foot ulceration 113 Volume 27 Number 3 – September 2019 wound healing by prolonging the inflammatory phase, decreasing fibroblast proliferation, and altering collagen synthesis17. However, dietary intake in patients with DFU has not yet been determined in an Australian cohort. With such variation in regional dietary intake, it is important that this can be established. Presence of infection will be determined by the International Working Group for the Diabetic Foot (IWGDF) guidelines for infection and will be collected by the treating podiatrist. Infection remains the most frequent diabetes complication requiring hospitalisation, and the most common precipitating event leading to lower extremity amputation18. This study will determine how much impact infection has on healing outcomes in DFU. Self-reported physical activity levels will be determined using the International Physical Activity Questionnaire (IPAQ), a validated research tool to determine physical activity levels19. Weight-bearing activity influences the amount of mechanical trauma in the plantar surface of the foot, and is a contributor to DFU20. Presence of foot deformity will also be collected, along with offloading intervention type, and wound education will be given. Current guidelines recommend that patients with DFU reduce their weight-bearing activities, in addition to wearing an offloading device to assist with healing21. Waist circumference will be determined using a tape measure, and weight and height measurements will also be taken to determine patients' body mass index. Obesity is associated with higher rates of post-operative wound infection, with reductions in tissue perfusion proposed as one contributing factor – adipose tissue is poorly vascularised and a reduction in collagen production is also frequently seen22. However, it is currently unclear how obesity impacts wound healing in patients with DFU. Neurological assessment will be performed using a combination of two tests, including a four-site monofilament test and measurement of vibration perception threshold by a neurothesiometer at the hallux. Ascertaining neurological status will help inform the aetiology of the DFU. Wound grade will be determined using University of Texas wound grade classification for DFU which involves assessing the size, depth and duration of the wound. Higher wound grades in chronic DFU are associated with higher rates of non-healing 23. Follow-up with participants regarding their wound healing will be completed at regular intervals through a clinical note audit at 3 and 6 months after the initial assessment, where wound size will be compared to the initial wound measurement.]]> Wed 10 May 2023 12:24:20 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:53721 Wed 10 Jan 2024 11:18:03 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:52150 Wed 04 Oct 2023 10:27:45 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:49013 Wed 03 May 2023 12:24:08 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:37741 0.2, with one study reporting a higher value of 0.8. Main conclusions: Successful post-amputation healing outcomes were reported at mean toe systolic blood pressure ⩾30 mmHg, and the results varied considerably between the studies. Further research should identify whether variables, including amputation level, method of wound closure and length of post-operative follow-up periods, affect the values of toe systolic blood pressure and toe-brachial pressure index observed in this review.]]> Wed 03 Aug 2022 10:31:15 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:36555 Tue 30 Jun 2020 11:51:34 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:43135 Tue 13 Sep 2022 15:21:30 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:54235 0.05). These secondary findings from a randomised controlled trial are the first data reporting the effect of exercise interventions on cutaneous microvascular reactivity in the foot in people with diabetes. A period of 12 weeks of moderate-intensity or low-volume high-intensity exercise may not be enough to elicit functional improvements in foot microvascular reactivity in adults with type 2 diabetes and obesity. Larger, sufficiently powered, prospective studies are necessary to determine if additional weight loss and/or higher exercise volume is required.]]> Tue 13 Feb 2024 13:20:24 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:45369 Thu 27 Oct 2022 15:02:10 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:48866 Thu 13 Apr 2023 10:01:04 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:52240 Thu 05 Oct 2023 11:54:15 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:52227 Thu 05 Oct 2023 10:29:54 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:11877 Sat 24 Mar 2018 10:31:25 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:12957 Sat 24 Mar 2018 08:18:28 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:16910 Sat 24 Mar 2018 07:59:51 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:26892 Sat 24 Mar 2018 07:41:40 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:27490 Sat 24 Mar 2018 07:25:38 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:22538 Sat 24 Mar 2018 07:14:47 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:38519 Mon 29 Jan 2024 17:55:30 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:20555 Mon 18 Mar 2019 12:45:01 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:48230 Mon 08 May 2023 10:28:01 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:52793 Fri 27 Oct 2023 14:08:39 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:39967 n = 39 of 111 participants or 35.1%) was associated with lower levels of self-perceived foot function (r = − 0.20, n = 107, p = 0.04). Conclusion: We found that community-based foot health care services that are culturally safe are utilised by Aboriginal and Torres Strait Islander Peoples not currently at high risk of foot complications. This supports the use of culturally safe foot care services to improve engagement with preventative foot care. Future research should continue to be driven by Aboriginal and Torres Strait Islander Peoples and investigate ways to implement additional screening measures and undertake prospective evaluation of the impact of such services on health related outcomes in these communities.]]> Fri 15 Jul 2022 10:18:34 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:51505 Fri 08 Sep 2023 11:56:03 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:52997 Fri 03 Nov 2023 16:07:56 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:32590  50% arterial obstruction was identified in any lower limb vessel using colour duplex ultrasonography. A receiver operating characteristic curve was analysed and the sensitivity and specificity of commonly used toe brachial index and toe blood pressure values were determined. Results: The optimum toe brachial index threshold value for diagnosing peripheral arterial disease was 0.72 (sensitivity 76.2%, specificity 75%). The area under the curve was 0.829 (95% CI 0.743 to 0.915, p < 0.0001) suggesting fair diagnostic accuracy. A toe blood pressure of 70 mmHg was found to have excellent specificity (97.92%) for detecting PAD but poor sensitivity (42.86%). Conclusions: The accuracy of automated toe blood pressure and TBI measurements was determined to be good when using colour duplex ultrasound as the reference standard for the non-invasive diagnosis of peripheral arterial disease. Results should be interpreted in the context of all clinical signs and symptoms.]]> Fri 01 Apr 2022 09:24:40 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:37445 Fri 01 Apr 2022 09:23:55 AEDT ]]>